Chapter 17 Microbiology The cellular immune response can seem a bit more complex
ID: 218000 • Letter: C
Question
Chapter 17 Microbiology
The cellular immune response can seem a bit more complex than the humoral response because there are more cell types involved and more than one outcome for many of these cell types. Let’s focus on the different T cell subtypes and their role in the cell-mediated response.
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Identify the following statements regarding cell-mediated immunity as either correct or incorrect
iPad? 8:58 PM a session.masteringmicrobiology.com Homepage- Introdu... Pearson MyLab and... Course Home MasteringMicrobi... foundation-fig-17-20... Chegg Study | Guide.. Chapter 17 Homework Dual Nature of the Adaptive Immune System Foundation Figure 17.20 1of5 ? ResetH The cell-mediated response functions to target and effectively remove freely circulating pathogens where antibodies can come in contact with them T helper cells aid in both the humoral and cellular immune responses The cellular immune response is mediated by T cells T cells, like B cells, are specific for a particular antigen CD8* T cells are T cytotoxic (Tc) cells that bind to MHC class I CD4+ T cells are helper cells that bind to the major histocompatibility molecules and can differentiate into complex (MHC) Il class molecules on primarily into two different subsets B cells and antigen-presenting cells The recognition of antigens by aT cell requires that an antigen- T helper (TH) cells differentiate presenting cell (APC) first processm TH1 and TH10 an effector cytotoxic T lymphocyte (CTL) them (APCs) T cells are classified by their clusters Cytotoxic T lymphocytes (CTLs) canof differentiation (CD), which serve as use perforin, a pore-forming protein to kill self cells that have been altered receptors. The most important CD classes for cell-mediated immunity are CD4 and CD6 by infection with a pathogen Correct statements Incorrect statementsExplanation / Answer
Q) The correct statements are :-
The cellular immune response is mediated by T cells.
T-cells like B-cells are specific for a particular antigen.
The recognition of antigens by T cell requires that an antigen presenting cell (APC) first process them.
Explanation- antigen-presenting cell (APC) or accessory cell are the cells that are antigen combined with major histocompatibility complexes (MHCs) on their surfaces, this process is known as antigen presentation. T cells recognize these complexes by T cell receptors (TCRs). These cells process the antigens and present them to T-cells.
CD8+ T cells are cytotoxic cells that bind to MHC class-1 molecules and can differentiate into an effector cytotoxic T lymphocyte (CTL).
Cytotoxic T lymphocytes (CTL) can use perforin, a pore forming protein to kill self cells that have been altered by infection with a pathogen.
The in-correct statements are as below:-
T helper cells help in both humoral and cellular immune response.
Explanation- T cells helps in humoral immune response in which antibodies produced by B cells destroy the extracellular microorganisms and prevent the spread of intracellular infections. The activation of B cells and their differentiation into antibody-secreting plasma cells is triggered by antigen and requires helper T cells.
Cell mediated response functions to target and effectively remove freely circulating pathogens , where antibodies can come in contact with them.
Explanation- cell mediated immune system do not involve antibodies, rather it takes the help of activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen.
T helper cells (TH) differentiate primarily into different subsets TH1, and TH 10 .
Explanation- T helper cells develop into TH1and TH2 also known as Type-I and Type-2 helper T cells .
T cells are classified by their clusters of differentiation (CD) which serve as receptors , the most important CD classes for cell mediated immunity are CD4 and CD6.
Explanation- T cells are classified by their clusters of differentiation (CD) which serve as receptors , the most important CD classes for cell mediated immunity are CD4 and CD8.
CD4+ cells are helper cells that bind to the MHC class-II molecules in B cells and antigen presenting cells.
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