Comparative Genomics. Answer the questions about these organisms: Homo sapiens;

Question

Comparative Genomics. Answer the questions about these organisms: Homo sapiens; Pan troglodytes, chimpanzee; Mus musculus, mouse; Canis lupus familiaris, dog; Escherichia coli (O157:H7, pathogenic) Use NCBI as your main source. https://www.ncbi.nlm.nih.gov/genome/ Browse by Oraganism a) What are the number of chromosomes and nucleotide bases pairs in each. b) What percentage of the human genome is shared with the other three organisms c) How many genes are there on each chromosome? d) How many base pairs and genes are there on the mitochondria for each of the organisms?

Explanation / Answer

a) Human have 23 pair of chromosome.

Chromosome 1

248.96 Mbp

Chromosome 2

242.19 Mbp

Chromosome 3

198.3 Mbp

Chromosome 4

190.22 Mbp

Chromosome 5

181.54 Mbp

Chromosome 6

170.81 Mbp

Chromosome 7

159.35 Mbp

Chromosome 8

145.14 Mbp

Chromosome 9

138.4 Mbp

Chromosome 10

133.8 Mbp

Chromosome 11

135.09 Mbp

Chromosome 12

133.28 Mbp

Chromosome 13

114.36 Mbp

Chromosome 14

107.04 Mbp

Chromosome 15

101.99 Mbp

Chromosome 16

90.34 Mbp

Chromosome 17

83.26 Mbp

Chromosome 18

80.37 Mbp

Chromosome 19

58.62 Mbp

Chromosome 20

64.44 Mbp

Chromosome 21

46.71 Mbp

Chromosome 22

50.82 Mbp

Chromosome X

156.04 Mbp

Chromosome Y

57.23 Mbp

Pan troglodytes (Chimpanzee)

Chromosome 1

2,993.16 Mbp

Chromosome 2A

224.24 Mbp

Chromosome 2B

128.76 Mbp

Chromosome 3

196.56 Mbp

Chromosome 4

189.15 Mbp

Chromosome 5

159.32 Mbp

Chromosome 6

168.37 Mbp

Chromosome 7

156.05 Mbp

Chromosome 8

143.34 Mbp

Chromosome 9

110.51 Mbp

Chromosome 10

129.81 Mbp

Chromosome 11

130.78 Mbp

Chromosome 12

131 Mbp

Chromosome 13

95.6 Mbp

Chromosome 14

87.72 Mbp

Chromosome 15

80.52 Mbp

Chromosome 16

75.91 Mbp

Chromosome 17

76.55 Mbp

Chromosome 18

74.77 Mbp

Chromosome 19

56.73 Mbp

Chromosome 20

64.04 Mbp

Chromosome 21

33.23 Mbp

Chromosome X

151.58 Mbp

Chromosome Y

26.35 Mbp

Mus musculus have 40 autosomal chromosome and 2 sex chromosome, Dog have 78 chromosome, Escherichia coli (O157:H7 ) have 1 circular chromosome have 4.64 bp.

b. Human and mouse have 85% identical genome, 98% with chimpanzee, 66% with dogs.

Chromosome 1

248.96 Mbp

Chromosome 2

242.19 Mbp

Chromosome 3

198.3 Mbp

Chromosome 4

190.22 Mbp

Chromosome 5

181.54 Mbp

Chromosome 6

170.81 Mbp

Chromosome 7

159.35 Mbp

Chromosome 8

145.14 Mbp

Chromosome 9

138.4 Mbp

Chromosome 10

133.8 Mbp

Chromosome 11

135.09 Mbp

Chromosome 12

133.28 Mbp

Chromosome 13

114.36 Mbp

Chromosome 14

107.04 Mbp

Chromosome 15

101.99 Mbp

Chromosome 16

90.34 Mbp

Chromosome 17

83.26 Mbp

Chromosome 18

80.37 Mbp

Chromosome 19

58.62 Mbp

Chromosome 20

64.44 Mbp

Chromosome 21

46.71 Mbp

Chromosome 22

50.82 Mbp

Chromosome X

156.04 Mbp

Chromosome Y

57.23 Mbp

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