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GENETICS: Please help explain C and D. Will give a thumb if given a good explana

ID: 263395 • Letter: G

Question

GENETICS:

Please help explain C and D. Will give a thumb if given a good explanation. I am confused with C and D.

43. You have come into contact with two unrelated patients who express what you think is a rare phenotype-a dark spot on the bottom of the foot. According to a medical source, this phenotype is seen in 1 in every 100,000 people in the population. The two patients give their family histories to you, and you generate the pedigrees that follow. a. Given that this trait is rare, do you think the in heritance is dominant or recessive? Are there any special conditions that appear to apply to the inheritance? must carry the mutant allele? pose for the inheritance? genotype normally causing the trait? b. Which nonexpressing members of these families c. If this trait is instead quite common in the popula- tion, what alternative explanation would you pro- d. Based on this new explanation in (c), which nonex- pressing members of these families must have the The Smiths 2 2 7 The Jeffersons 1 2 1 2 3 4 5 67 1 2 3 4 5 6

Explanation / Answer

GENETICS: Please help explain C and D. Will give a thumb if given a good explana