A study was conducted to determine the effect of the addition of a particular su
ID: 3066020 • Letter: A
Question
A study was conducted to determine the effect of the addition of a particular supplement to a well-known low-density lipoprotein (LDL) cholesterol-lowering drug. Five thousand randomly selected patients were studied on this combination of drugs over a 1-year period. An increased reduction of 5 mg/dL of LDL cholesterol was achieved with the combination of drugs relative to the well-known drug alone. The reduction resulted in a P-value of 0.001.
A)
This P-value result shows that the combination drug should be prescribed widely.
B)
Clearly, this study has demonstrated the effectiveness of this new treatment.
C)
The result should be viewed with caution because 1 year is not a long time to study such an important matter as cholesterol.
D)
A sample of this size can detect very small differences and hence care should be taken to determine if a reduction of this amount has any practical significance with respect to LDL cholesterol reduction.
E)
A sample of this size will be able to demonstrate how good the new drug combination really is with very large probability.
A study was conducted to determine the effect of the addition of a particular supplement to a well-known low-density lipoprotein (LDL) cholesterol-lowering drug. Five thousand randomly selected patients were studied on this combination of drugs over a 1-year period. An increased reduction of 5 mg/dL of LDL cholesterol was achieved with the combination of drugs relative to the well-known drug alone. The reduction resulted in a P-value of 0.001.
A)
This P-value result shows that the combination drug should be prescribed widely.
B)
Clearly, this study has demonstrated the effectiveness of this new treatment.
C)
The result should be viewed with caution because 1 year is not a long time to study such an important matter as cholesterol.
D)
A sample of this size can detect very small differences and hence care should be taken to determine if a reduction of this amount has any practical significance with respect to LDL cholesterol reduction.
E)
A sample of this size will be able to demonstrate how good the new drug combination really is with very large probability.
Explanation / Answer
Solution:- E) A sample of this size will be able to demonstrate how good the new drug combination really is with very large probability.
As the sample size increases the value of test statistics tends to decrease but as per given p-value the test statistic still have higher value, hence we can say that new drug is very effective.
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