I need this article to be summarized in simple note form or in a summary form pl
ID: 3481020 • Letter: I
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I need this article to be summarized in simple note form or in a summary form please.
Abstract Purpose: Many breast cancer patients gain weight during chemotherapy and antiestrogenic treatment increasing recurrence, oncologic specific and all-cause mortality risks. Patients and Methods: 165 ER+/PR/HER2- breast cancer patients under antiestrogenic treatment were randomly assigned to follow an at-home diet based on food naturally high in proteins, calcium, probiotics and prebiotics (D), or this diet and 4' isometric exercises (D+Ex) for 1 year. We measured weight (W), body (BF) and visceral fat (VF) using a multi-frequency bioelectrical impedance scale on the 6th and 12th month and we correlated results with chemotherapy, surgery and antiestrogenic medication type. Results were analysed using the Friedman Test, then with Wilcoxon signed-rank tests if Friedman Test was significant. Results: Overall, the patients' 1-year results show that both D+Ex and D patients obtained statistically significant weight loss and fat loss. D patients lost 3.3 kg, 3.2% BF and 1% visceral fat. D+Ex patients lost 6.5 kg, 3.3% BF and 2% visceral fat. D+Ex patients obtained sta- tistically significance for W, BF and VF regardless of chemotherapy, surgery or antiestrogenic treatment type. D patients with mastectomy or with aromatase inhibitors lost W, BF and VF. D patients with conservatory surgery, adjuvant or both neoadjuvant and adjuvant chemotherapy and those on Tamoxifen only lost W. D patients with neoadjuvant chemotherapy also lost VF. Conclusion: This diet is effective for ER+/PR/HER2- breast cancer patients on antiestrogenic medication. Adding at least a minimal exercise protocol improves patients' chances of counteracting sarcopenic obesity. Key words: breast cancer, sarcopenic obesity, oncology nutrition, isometric exercise Introduction Besides, overeating or eating regardless of physical hunger; which are the main weight Breast cancer patients, who gain weight gain causes – insulin and leptin resistance, during treatment, have a higher risk of all dysbiosis and dyslipidemia – are potentially cause and oncologic specific mortality, de novo aggravated during breast cancer chemotherapy carcinogenesis and recurrence. (1) by sarcopenia. (2) In addition, studies proveExplanation / Answer
the article is explaining about the weight gaining after cancer treatment by chemotherapy this can leads to mortality
so they observed the patients with chemotherapy and chemo+excercise patients among these chemo+excercise patients are loosing more body and viseral fat so they are less prone to mortality.coming to the only chemo patients without excersice they loosing less weights and becoming more fatty when compared to chemo+excercise patients this becomes more prone to mortality
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