4 How can you transcribe and translate a gene? continued Key U UUU Phe UAU-Tyr y

Question

4 How can you transcribe and translate a gene? continued Key U UUU Phe UAU-Tyr ys U RNA Bases UUC-Phe UCC-Ser UUA-Leu A adenine, C cytosine, G guanine, U urad UCA-Ser CCU Pro CCA-Pro ACU-Thr UGA-stop A Amino Acids: UUG-Leu UAG-Stop UCG TP G CAU His C CUU-Leu CGU-Arg CGC-Arg cl_t: methionine, CGA-Arg A Ser serine, U-= isoleucine, C Val-valine, CUC-Leu CCC Pro CUG Leu CCG Pro Thr threonine, A AUUlle AAU Asn AGU-Ser U Ala alanine, AUC-lle ACC-Thr AAC-Asn AGC-Ser Cis AUA-lle ACA-Thr AAA-Lys AGA Arg A Gin glutamine Lys-lysine, Glu glutamic acid, G GUU-Va GGU-Gly U Asp aspartic acid, GUC-Val GCC-Ala GUA-Val GCA-Ala GUG-Val GCG-Ala GAC-Asp GGC-Gly C Cys cysteine, GGA-Gly A Trp -tryptophan Arg- arginine, GAG-Glu GGG-GlyG Gy - glycine Part B: Translating and Transcribing DNA Sequences for Known Hemoglobins Part A: Transcribing and Translating Mystery DNA Sequences 5. Repeat steps 2-4 to determine the sequence of the first nine amino acids encoded in the DNA for normal hemoglobin (normal Hb). Record 1. You have been given two mystery your results under Data and Observations DNA sequences, shown under Data and Observations. One of them codes for some of 6. A point mutation in the seventh codon for the amino acids in a known human protein. Transcribe and translate the mystery DNA sequences to identify the amino acid sequence nucleotide base results in the amino acid valine encoded in each, following steps 2-4. Record your work under Data and Observations normal hemoglobin produces sickle-cell hemoglobin (Hb S). A change in a single in this position. Record the sequence of the Data and variants, induding hemoglobin first nine amino acids in hemoglobin S 2. First, transcribe each DNA sequence by 7. There are many other known hemoglobin writing the corresponding sequence of complementary bases in the m RNA molecule which has lysine instead of glutamic acid in position seven, and hemoglobin G (Hb G) which has glycine instead of glutamic acid in position eight. Record the sequences of first nine amino acids in hemoglobins C and G under Data and Observations 3. Then, translate each mRNA sequence into a complementary sequence of tRNA anticodons. 4. Finally, use the genetic code to translate the mRNA sequence into the correct sequence of amino acids

Explanation / Answer

1) The mystery DNA sequence #1 matches with the normal hemoglobin sequence. It is normal hemoglobin.

2) The normal hemoglobin have the amino acid methionine (Met) which have only code AUG also called initiation codan . If this codan is replaced by GUG which is also initiation codan then it takes place as point mutation beacaun only one neclicacid will be changed "A" replaced by "G" and results into methionine will be replaced by Valine( Val).

Related Questions

Navigate

• Browse (All)
• Browse 4
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.