Academic Integrity: tutoring, explanations, and feedback — we don’t complete graded work or submit on a student’s behalf.

1. Indicate whether it is the neuromuscular junction at rest or active (in the p

ID: 3513184 • Letter: 1

Question

1. Indicate whether it is the neuromuscular junction at rest or active (in the process of transmitting a signal); neuromuscular junction at rest & neuromuscular junction active

- Na+ diffusion

- Calcium channels open

- More negative charges inside sarcolemma

- Calcium channels closed

- Chemically-gated channels open

- ACh in synaptic cleft

- No Na+ diffusion

- Less negative charges inside sarcolemma

- ACh in synaptic vesicles

- Chemically-gated channels closed

2. Match term to the appropriate definition.

Terms:

- Acetylcholine

- Synaptic vesicle

- Acetylcholinesterase

- Sodium channel

- Acetylcholine receptor

- Calcium channel

- Synaptic cleft

Definitions:

- Neurotransmitter that stimulates skeletal muscle contraction.

- Membranous sac located in the axon terminal that contains neurotransmitter.

- Enzyme located in the synaptic cleft that breaks down acetylcholine.

- A type of voltage-gated ion channel located on the axon terminal.

- The space between the axon terminal and junctional folds.

- A type of voltage-gated ion channel located on the sarcolemma of the muscle fiber.

- A type of chemically-gated ion channel located on the junctional folds of the muscle fiber.

Explanation / Answer

Answer 1

Na+ diffusion - active

Calcium channel open- active

More Negative charges inside sarcolemma- inactive

Calcium channel closed - inactive

Ach in synaptic cleft -active

No Na+ diffusion - inactive

Less negative charges inside sarcolemma- active

Ach in synaptic vesicle - inactive

Chemically gated channels closed - inactive

Answer 2

Acetylcholine- a neurotransmitter that stimulates skeletal muscle contraction.

Synaptic vesicle- membranous sac located in axon terminal that contains neurotransmitter

Acetylcholinesterase - enzyme that breaks acetyl choline in synaptic cleft

Sodium channels- type of voltage gated channel located on axon terminal

Ach receptor- a type of chemically gated ion channel located on the junctional folds of the muscle fibre.

Calcium channel- a type of voltage gated channel located on sarcolemma of the muscle fibre

Synaptic cleft- space between the axon terminal and junctional folds