A loss of function mutation in lin-3, a gene that provides the inductive signal
ID: 42468 • Letter: A
Question
A loss of function mutation in lin-3, a gene that provides the inductive signal from the anchor cell to vulval precursor cells, will result in what phenotype?
Multiple vulva develop because none of the precursor cells are induced.
Multiple vulva develop because multiple the precursor cells are induced.
No vulva develop because multiple precursor cells are induced.
No vulva develop because none of the precursor cells are induced.
Multiple vulva develop because none of the precursor cells are induced.
Multiple vulva develop because multiple the precursor cells are induced.
No vulva develop because multiple precursor cells are induced.
No vulva develop because none of the precursor cells are induced.
Explanation / Answer
lin 3 gene encodes epidermal growth factor which is tyrosine kinase receptor induces vulva development through Ras signal transduction pathway. In this pathway, the gene encodes the anchor cell that induces the vulva development. In this pathway the loss- of - function mutation results in mutant phenotype that contains defect in vulva development. Therefore, the mutation, results in phenotype with no vulva develop because none of the precursor cells are induced.
Hence, the option 4 is correct.
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