What is the fundamental reaction of RNA synthesis? (a) formation of correct base

Question

What is the fundamental reaction of RNA synthesis? (a) formation of correct bases especially uracil (b) formation of ribosyl linkages (c) formation of a phosphodiester bond (d) hydrolysis of the pyrophosphate to orthophosphate (e) unwinding the double-stranded DNA

What causes point mutations? (a) Formation of free radicals (b) Altered bases (c) intercalating agents (d) both a and b (e) both a and c

Which of the following biomolecules aids in termination of prokaryotic transcription? (a) rho protein (b) sigma subunits (c) promoters (d) cis-acting elements (e) trans-acting elements

Why are apurinic sites highly cytotoxic in mammalian DNA? Because a. AP sites can irreversibly trap topoisomerase I in its covalent complex with DNA b. ribose at the AP site lacks a glycosidic bond and can readily convert to its linear form, whose reactive aldehyde group can cross-link to other cell components c. AP sites remain tightly bound to uracil DNA glycosylase in solution d. a and b e. a and c

Explanation / Answer

The fundamental reaction of RNA synthesis is the formation of a phosphodiester bond

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