Consider the following individuals in a-c below. First, write out the genotype o

Question

Consider the following individuals in a-c below. First, write out the genotype of each individual described (define allele symbols) then use a fork-lined diagram to determine ail possible gamete types: A female that is heterozygous for an X-linked gene A, homozygous for a mutant allele of gene B on chromosome I and heterozygous for gene C on chromosome II (define your symbols): A female that is heterozygous for two X-linked genes A and B (they are found in the repulsion conformation) and heterozygous for an autosomal gene C. A may that is hemizygous for mutant alleles of genes A and B (both linked to the X chromosome and heterozygous for an autosomal gene C.

Explanation / Answer

a] XA = wild type , Xa = mutant, b= mutant, C= wild type, c = mutant  

XA Xa bb Cc

C------->b -------> XA C b

XA

c---------> b -----> XA c b

C------->b -------> Xa C b

Xa

  c---------> b -----> Xa c b

b] This one would be like in repulsion state - XA Xb / Xa XB Cc. Gametes would be-

C ----------> XA Xb C

XA Xb

c-------------> XA Xb c

C ------------> Xa XB C

Xa XB

c -------------> Xa XB c

c] Male is hemizygous, that means single allele of each gene is present. Genotype will be- Xab / Y Cc.

Xab = mutant forms of genes A and B, Y = Y chromosome C = wild type, c = mutant

Gametes would be-

C --------------> Xab C

Xab

c --------------> Xab c

C ------------> Y C

Y

c ------------> Y c

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