What would be the most likely consequence if each origin of replication initiate

Question

What would be the most likely consequence if each origin of replication initiated multiple times during S-phase of the cell cycle in a human cell?

A.No consequence

B.Aneuploidy

C.Inappropriate activation of Cdks

D. Longer chromosomes

E. Sister chromatids could not separate

I chose C and I got it wrong. I know that the S-phase involves the replication process, but my next guess would be A. Please give the answer you think is correct with an explanation. I would really like to understand and will rate!

Explanation / Answer

D. Longer chromosomes

Generally, the origin of replication is initiated at multiple sites on multiple chromosomes, which results in the replication of larger chromosomes with high accuracy. However, the activation of origin of replication sites occurs only once, which gives the genome of specific size. If these sites are activated multiple times, longer chromosomes would result (because the same site replicates multiple times).

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