Consider a locus with two codominant alleles, A and B In a population of 100, th

Question

Consider a locus with two codominant alleles, A and B In a population of 100, there are 35 AA, 50 AB and 15 BB In this population, AA individuals have on average 2 5 kids, AB individuals have on average 2 8 kids and BB individuals have an average of 23 What is the gene frequency for the A allele? What is the relative fitness of the BB genotype? What is the selection coefficient acting on the AA genotype? Using the appropriate equation found on the chart on the last page of this exam predict the gene frequency for allele B in the next generation. Briefly explain why genetic drift is inevitable even in large natural populations Be sure to use appropriate terminology.

Explanation / Answer

a. allelic frequency of A=0.6

b.relative fitness of BB genotype =0.82

c.selection coefficient of Aa genotype =0.11

genotype no. of individuals genotypic frequency allelic frequency (square root of p2 or q2) relative fitness (w) selection coefficient (S)= (1-w) AA 35 0.35 0.35+0.5/2=0.6 2.5/2.8 = 0.89 1-0.89 =0.11 AB 50 0.5 2.8/2.8 = 1 1-1 =0 BB 15 0.15 0.15+0.5/2=0.4 2.3/2.8= 0.82 1-0.82=0.18

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