What is the probability II-2 is a carrier of the disease (number between 0 and 1

Question

What is the probability II-2 is a carrier of the disease (number between 0 and 1)?

II-1 and II-2 are expecting a child. The sonogram shows they will be having a son. What is the probability he will develop the disease late in life?

II-1 and II-2 have their son. At an early age, it is apparent that he is color-blind. What is the chance he will develop the disease late in life?

disease DEB color blind pedigree color blind and disease A recessive trait for a late-onset neurological disease is located 8 map units from the recessive deutan color blindness trait, on the X chromosome. Below is a pedigree from a family in which both traits are found. The woman's husband is color-blind, and she has two sons who show the disease but are not color blind. Her daughter shows neither trait, and is well past the age where the symptoms appear.

Explanation / Answer

1. If II-2 must be a carrier then the probability is 1, that the individual is a career.

2. The probability of the son between II-1 and II-2 (career woman) to have the disease is 0.5.

3. Though, he has been identified as color-blind at an early age, the chance he will develop the disease late in life would be 0.5.

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