In a regular physical check, Peter received a doctoral report, which stated that
ID: 3305092 • Letter: I
Question
In a regular physical check, Peter received a doctoral
report, which stated that “The test for lupus indicates that
you may have it. However, about 5% normal population
without lupus test positive. We will arrange more accurate
DNA-based test for you. Please contact our office for an
appointment.” Lupus is a chronic autoimmune disease
characterized by inflammation in one or more parts of the
body. Peter was very worried and found out that on
average 1 out of every 1000 Canadians suffer lupus (see
http://www.lupuscanada.org/). Suppose that the test used
by the doctor can identify 100% of the patients with lupus.
Based on the numbers given above, can you find the
chance that Peter does have lupus? Your calculation may
save him from many sleepless nights before he receives
the accurate DNA-based test result.
Explanation / Answer
P(Lupus) = 1/1000 = 0.001
So,
P(Not Lupus) = 1 - 0.001 = 0.999
P(Positive| Lupus) = 1
P(Positive| Not Lupus) = 0.05
So,
P(Lupus| Positive)
= (0.001*1)/(0.001*1 + 0.999*0.05)
= 0.0196
So,
There is only 1.96% chance that Peter has it if the test says that he may have it.
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